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Left ventricular (LV) concentric remodeling refers to a process by which increased LV relative wall thickness alters myocardial geometry, resulting in reduced LV end-diastolic volume (LVEDV) and stroke volume (SV).
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Remodelling of the left ventricle is one of the most important pathophysiological processes in heart failure. Four basic patterns of left ventricular (LV) remodelling have been recognized: normal geometry, concentric remodelling, concentric hypertrophy and eccentric hypertrophy.Under pressure overload, remodeling is primarily concentric because of the addition of myocyte sarcomeres in parallel. 5 Therefore, LV wall thickness increases to a greater extent than the volume of the LV cavity; as a result, the ratio of LV mass to end-diastolic volume (M/V ratio) increases.
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